Phosphohistidine phosphatase sixa
WebResearch in the field of protein-bound phosphohistidine phosphorylation has been hampered by the difficulties in analysis and detection of phosphohistidine. Therefore a screening method was developed primarily for the analysis of phosphohistidine phosphatase 1 (PHPT1) activity. Methods. A highly positively charged substrate, Ac-Val … WebThe sixA gene encodes a phosphohistidine phosphatase that specifically removes the phosphoryl group from the His717 residue of ArcB . [More information is available at EcoCyc: G7211]. Other designations phosphohistidine phosphatase SixA GeneRIFs: Gene References Into Functions
Phosphohistidine phosphatase sixa
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WebNov 10, 2006 · SixA shows structural homology to the well studied family of arginine-histidine-glycine (RHG) phosphatases but no sequence homology to PHPT1. Mammalian phosphohistidine phosphatase (PHPT1) was first identified and characterized as a 14-kDa protein in 2002 (7, 8). WebMar 1, 2002 · Such a phosphohistidine phosphatase, if present, should also serve as a modulator for the His-Asp phosphorelay. In this study, we intended to find such a …
Webphosphohistidine phosphatase SixA. Gene provides a unified query environment for genes defined by sequence and/or in NCBI's Map Viewer. sixA phosphohistidine phosphatase SixA [] Gene ID: 11772935, updated on 23-Sep-2024. Summary. Other designations. phosphohistidine phosphatase SixA ... WebSixA was first reported to be a phosphohistidine phosphatase that dephosphorylates the histidine-containing phosphotransfer domain of the E. coli sensor kinase ArcB ( 32 , 41 ), …
WebExpression profile; Y-axis: expression values, x-axis: tissues/treatments. Red dots: average expression, green dots: expression from individual microarray/RNAseq experiments. WebNov 27, 2024 · SixA, a well-conserved protein found in proteobacteria, actinobacteria, and cyanobacteria, is the only reported example of a bacterial phosphohistidine phosphatase. …
WebJan 1, 2024 · We show that the phosphatase SixA dephosphorylates the phosphocarrier protein NPr and that the reaction proceeds through phosphoryl transfer from a histidine on NPr to a histidine on SixA. In addition, we show that Escherichia coli lacking SixA are outcompeted by wild-type E. coli in the context of commensal colonization of the mouse …
WebNov 27, 2024 · SixA, a well-conserved protein found in proteobacteria, actinobacteria, and cyanobacteria, is the only reported example of a bacterial phosphohistidine phosphatase. A single protein target of SixA has been reported to … church corner house haywards heathWebSep 27, 2024 · The K Ca 3.1 auxiliary subunits that positively or negatively control its activity as well as T-cell function have been identified: phosphoinositide-3-kinase, class 2, β polypeptide (PI3K-C2B), nucleoside diphosphate kinase-B (NDPK-B), phosphohistidine phosphatase 1 (PHPT1), myotubularin-related protein 6 (MTMR6), tripartite motif … church corner shoe repairsWebNov 27, 2024 · SixA, a well-conserved protein found in proteobacteria, actinobacteria, and cyanobacteria, is the only reported example of a bacterial phosphohistidine phosphatase. … deus me ama thalles roberto letraWebA widely conserved phosphohistidine phosphatase was identified in Escherichia coli twenty years ago but remains relatively understudied. This bacterial protein is called signal … deus online shopWebFeb 10, 2024 · Our results suggest a model in which SixA removes phosphoryl groups from the nitrogen-related phosphotransferase system by acting on NPr. This work uncovers a new role for the phosphohistidine phosphatase SixA and, through factors that affect SixA expression or activity, may point to additional inputs that regulate the nitrogen-related ... church corner much marcleWebThe sixA gene encodes a phosphohistidine phosphatase that specifically removes the phosphoryl group from the His717 residue of ArcB . [More information is available at … churchcorners.orgWebNov 10, 2006 · The structure of phosphohistidine phosphatase (PHPT1) has been determined to a resolution of 1.9Å using multiple-wavelength anomalous dispersion methods and Histidine 53 is proposed to play a major role in histidine dephosphorylation based on these observations and previous mutational studies. deus proverá shirley letra