Phosphogluconate 2-dehydrogenase
WebThe pentose phosphate pathway (PPP) plays an essential role in the metabolism of breast cancer cells for the management of oxidative stress and the synthesis of nucleotides. 6-phosphogluconate dehydrogenase (6PGD) is one of the key enzymes of the oxidative branch of PPP and is involved in nucleotide biosynthesis and redox maintenance status. … WebJan 25, 2006 · Phosphogluconate dehydrogenase (EC:1.1.1.44) is a key enzyme in the cytosolic oxidative branch of the pentose phosphate pathway ( 6 ), and catalyzes the second oxidative reduction of NADP+ to NADPH ( 2, 7, 1 ).
Phosphogluconate 2-dehydrogenase
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WebJun 21, 2024 · (e.g. Trx m2).2,3 In case of the first OPPP step, catalyzed by glucose-6-phosphate dehydrogenase (G6PDH), the plastidial Arabidopsis isoform G6PD1 is retained in the cytosol through interaction with G6PD4 (another redox-responsive but catalytically inactive plastidial isoform), followed by folding and peroxisomal import of G6PD1 upon … WebMay 25, 2024 · DOI: 10.1016/j.molbiopara.2024.111383 Corpus ID: 235241530; Cloning, purification, and characterization of the 6-phosphogluconate dehydrogenase (6 PGDH) from Giardia lamblia. @article{MoralesLuna2024CloningPA, title={Cloning, purification, and characterization of the 6-phosphogluconate dehydrogenase (6 PGDH) from Giardia …
• Frampton EW, Wood WA (October 1961). "Carbohydrate oxidation by Pseudomonas fluorescens VI. Conversion of 2-keto-6-phosphogluconate to pyruvate". The Journal of Biological Chemistry. 236: 2571–7. doi:10.1016/S0021-9258(19)61700-X. PMID 13894458. WebJan 23, 2007 · Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO 2, with concomitant reduction of NADP to NADPH. By similarity …
WebAccepted name: phosphogluconate 2-dehydrogenase Other names: 2-keto-6-phosphogluconate reductase 6-phosphogluconate dehydrogenase (NAD) 6-phosphogluconic dehydrogenase gluconate 6-phosphate dehydrogenase phosphogluconate dehydrogenase 6-phosphogluconate 2-dehydrogenase Systematic name: 6-phospho- D … WebHaemophilus parasuis (H. parasuis) is a swine pathogen responsible for the Glässer’s disease. In order to understand the pathogenesis of the H. parasuis infection, the gnd gene encoding a cell surface protein, 6-phosphogluconate-dehydrogenase (6PGD) of H. parasuis was inducibly expressed in Escherichia coli BL21 with a hexahistidyl N-terminus to permit …
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