Des-γ-carboxy-prothrombin

Author: bcur

August undefined, 2024

WebProtein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II), also known as Des-γ-carboxy-prothrombin (DCP), is an abnormal form of prothrombin. Normally, the prothrombin’s 10 glutamic acid residues (Glu) in the γ-carboxyglutamic acid (Gla) domain at positions 6, 7, 14, 16, 19, 20,25, 26,... WebDec 20, 2014 · Purpose Alpha-fetoprotein (AFP) and des-γ-carboxy prothrombin (DCP) are prognostic factors for hepatocellular carcinoma (HCC). The impact of these tumor markers in recurrent HCC on the prognosis remains to be fully elucidated. Methods Two hundred and seventeen patients whose AFP and DCP levels were measured at …

DCP - Overview: Des-Gamma-Carboxy Prothrombin, Serum

WebBackground: The role of des-γ-carboxy prothrombin (DCP) in patients undergoing radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) needs to be clarified. Materials and methods: 174 HCC patients that underwent RFA were enrolled. We calculated the HLs of DCP from the available values before and on first day after ablation and ... WebObjective: To investigate the diagnostic value of des-γ-carboxy prothrombin (DCP) for recurrence in hepatocellular carcinoma (HCC) patients receiving precautionary sorafenib after curative liver resections. Methods: Eighty-five patients receiving curative hepatectomy and adjuvant sorafenib afterwards were enrolled. birthday signs for yards

PIVKA II (6C4), mAb, Mouse - GenScript

WebDes-γ-Carboxy Prothrombin. Serum concentrations of des-γ-carboxy prothrombin (DCP) (also known as prothrombin produced by vitamin K absence or antagonist II) are raised in most patients with HCC. 65 DCP is an abnormal prothrombin that is thought to result from a defect in the post-translational carboxylation of the prothrombin precursor … WebDes-γ-carboxy prothrombin (DCP), also referred to as protein induced by vitamin K absence (PIVKA-II), is a nonfunctional precursor of prothrombin. 7 Prothrombin, … WebDes-γ-carboxy prothrombin (DCP), an aberrant prothrombin produced by hepatocellular carcinoma (HCC) cells, has been shown to be associated with the … dante white leather power reclining sofa

The role of des-γ-carboxy prothrombin levels in hepatocellular ...

141325: Des-γ-carboxy Prothrombin (DCP) Labcorp

WebSaito M, Seo Y, Yano Y, Miki A, Yoshida M, Azuma T. A high value of serum des-γ-carboxy prothrombin before hepatocellular carcinoma treatment can be associated with long-term liver dysfunction after treatment. J. Gastroenterol. 2012; 47 (10):1134–1142. doi: 10.1007/s00535-012-0577-0. [Google Scholar] WebMar 4, 2015 · Des-γ-carboxy prothrombin (DCP), also kn own as “ protein induced by vitamin K absenc e or antagonist-I I ” (PIVKA-II), is an abnorma l prothrombin that has be en widely used as a tumor dante with accentWebNov 1, 1991 · Abnormal (des-γ-carboxy) prothrombin, defined as a protein induced by vitamin K absence or antagonist-II (PIVKA-II) was measured in the cases with hepatocellular carcinoma by a newly developed ... dante with a mustache

"WebIt remains unclear whether hepatocellular carcinoma (HCC) recurrence in hepatitis C virus (HCV)-infected patients can be suppressed by the elimination of the virus using direct-acting antivirals (DAAs) after radical HCC treatment. We evaluated the sustained inhibitory effect of DAAs on HCC recurrence after curative treatment. This multicenter retrospective study … " - Des-γ-carboxy-prothrombin

Des-γ-carboxy-prothrombin

DCP - Overview: Des-Gamma-Carboxy Prothrombin, Serum - mayoclinic…

WebObjectives: The aim of this study was to investigate the relationships between early changes in the tumor markers α-fetoprotein (AFP) and des-γ-carboxy prothrombin (DCP), and antitumor response in the early period following administration of sorafenib in patients with advanced hepatocellular carcinoma (HCC). Methods: Forty-eight advanced HCC patients … WebApr 10, 2009 · α-Fetoprotein (AFP) is widely used as a surveillance test for hepatocellular carcinoma (HCC) among patients with cirrhosis. Des-γ carboxy-prothrombin (DCP) and lectin-bound AFP (AFP-L3%) are potential surveillance tests for HCC. The aims of this study were to determine performance of DCP and AFP-L3% for the diagnosis of early HCC; …

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WebPatients were also more likely to have a fibrosis-4 (FIB-4) index > 3.25, Child–Pugh class A, and higher serum levels of alpha-fetoprotein and Des-γ-carboxy prothrombin (DCP). They were treated with sorafenib ( n = 275), lenvatinib ( n = 48), or ATZ/BV ( n = 36) as first-line therapy for advanced HCC. WebApr 1, 2008 · We measured plasma abnormal prothrombin (des-γ-carboxy prothrombin; DCP) levels in normal subjects and in patients with hepatocellular carcinoma and other various diseases using the enzyme-linked ...

WebNov 20, 2024 · A des-gamma-carboxy prothrombin (DCP) test may be used along with other tumor markers such as an alpha ... Bertino N, Boemi PM. 2010. Prognostic and … WebWe detected des-γ-carboxy prothrombin, an abnormal prothrombin, in the serum of 69 of 76 patients (91 per cent) with biopsy-confirmed hepatocellular carcinoma (the mean level of the abnormal ...

WebDec 4, 2003 · Des-γ-carboxy prothrombin (DCP) is useful as a marker of hepatocellular carcinoma (HCC). However, because of its low sensitivity, DCP is not suitable for the … WebNov 19, 2000 · Des-γ-carboxy prothrombin (DCP) is a useful tumor marker for hepatocellular carcinoma (HCC). The conventional enzyme immunoassay (EIA) kit for DCP lacks adequate sensitivity to detect small …

WebNov 29, 2015 · Determining the serum des-γ-carboxy-prothrombin (DCP) level is of great importance for the diagnosis of primary hepatocellular carcinoma (PHC). Although several studies have investigated the accuracy of diagnostic DCP tests for PHC, the results have been inconsistent. The aim of this study was to systematically evaluate DCP as a …

WebJan 26, 2007 · There is no established clinical role for the lens culinaris agglutinin-reactive fraction of α-fetoprotein (AFP-L3%) and des-γ-carboxy prothrombin (DCP) in the management of the U.S. hepatocellular carcinoma (HCC) patient population. In order to clarify the clinical usefulness and characteristics of AFP-L3% and DCP, a prospective … birthday signs printableWebDec 4, 2003 · Des-γ-carboxy prothrombin (DCP) is useful as a marker of hepatocellular carcinoma (HCC). However, because of its low sensitivity, DCP is not suitable for the initial detection of small HCC tumors. 1, 2 Recently, a sensitive method for serum DCP determination has been developed and reportedly is positive in 30–40% of patients with … birthday signs with candyWebThe utility of AFP is limited by low sensitivity and specificity. 166 Many other serum biomarkers, such as des-γ-carboxy prothrombin, are becoming available, but their usefulness remains to be proved. Serum AFP level and US of the liver are recommended every 6 months for screening of patients at risk of developing HCC. 167. birthday signs zodiac datesWebDes-γ-carboxy prothrombin (DCP) is a prothrombin precursor produced in hepatocellular carcinoma (HCC). Because of deficiency of vitamin K or γ-glutamyl … dante with hatWebOct 31, 2000 · Serum concentrations of des-γ-carboxy prothrombin (DCP) from 91 patients with hepatocellular carcinoma (HCC) and 57 with cirrhosis (LC) are shown. There is a statistically significant difference between the serum concentrations of DCP in HCC (48.3 ± 24.3, mean ± standard deviation) and those in cirrhosis (20.3 ± 10.3), as determined by … birthday signs zodiac febWebApr 24, 2002 · Serum des-γ-carboxy prothrombin (DCP) is a useful marker for the diagnosis of hepatocellular carcinoma (HCC), but the exact mechanism of its synthesis … dante with glassesWebFeb 12, 2024 · Background: The role of des-γ-carboxy prothrombin (DCP) in patients undergoing radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) needs to be clarified. Materials and methods: 174 ... birthday signs zodiac